The birth of the first child with DNA from three different people has taken place in the UK. MDT, for it was through this method that this could happen, is a procedure carried out before in vitro fertilization. It allows the creation of an embryo with genetic material from three different people: the mother, the father and the mitochondrial donor.
UK: Birth of a child with three DNAs
Published May 15, 2023 13:02
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MDT involves transferring healthy mitochondrial DNA from a donor cell to an egg cell or embryo of a woman with damaged mitochondria. With this procedure, most of the key genetic information comes from the father and mother, and only a small percentage of the donor's mitochondrial DNA is present. This prevents the development of severe mitochondrial diseases in children.
In 2015, the UK pioneered the establishment of regulations governing methods to prevent the transmission of genetic defects associated with damaged mitochondria in cells. The first baby born through the MDT technique was born in 2016 in the United States.
Although the MDT technique has received criticism, proponents argue that it is an effective tool in preventing the transmission of genetic diseases. Before the method is widely accepted, scientific research will continue to monitor possible side effects and evaluate the long-term health of children born using the technology.
The introduction of MDT in the UK and the subsequent birth of children with the DNA of "three people" are opening up new perspectives in the medical field, increasing the chances for families affected by mitochondrial diseases to have healthy offspring.
Some experts question its experimental nature and safety for offspring. There are also concerns about the ethical and moral aspects of genetic manipulation and the possibility of introducing social inequality. Critics also point to the existence of other proven methods of avoiding genetic diseases that do not require such interference.
Source: Guardian
