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Dr. Marek Derkacz, MBA

LDN may help recovery from stroke

MedExpress Team

Dr n. med. Marek Derkacz

Published May 16, 2023 11:05

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The latest online edition of the journal Neurochemical research published an article titled: "Acute Low Dose Naltrexone Increases β-Endorphin and Promotes Neuronal Recovery Following Hypoxia-Ischemic Stroke in Type-2 Diabetic Mice." The article shows that low-dose naltrexone therapy (LDN therapy) increases β-endorphin levels and promotes neuronal recovery after hypoxia and ischemic stroke in type-2 diabetic mice.

Stroke is estimated to affect several million people worldwide each year. According to WHO data, it is one of the most common causes of death and disability. While 10-15% of all cases are hemorrhagic strokes, the vast majority, about 85-90% of strokes, are ischemic.

Jak wygląda sytuacja w naszym kraju? W Polsce co osiem minut ktoś przechodzi udar mózgu, zaś każdego roku dotyka on około 75 tysięcy Polaków. Niestety ponad 30 tysięcy chorych umiera z powodu udaru mózgu, a to oznacza, że około 45 tysięcy zmaga się z jego ciężkimi następstwami, niekiedy nawet do końca życia. Niedokrwienie mózgu stanowi w naszym kraju trzecią najczęstszą przyczynę zgonów, zaraz po chorobach serca i nowotworach.

Diabetes, both type 1 and type 2, can increase the risk of ischemic stroke. The disease adversely affects the condition of blood vessels, accelerates vascular atherosclerosis, which increases the risk of thrombus formation in the circulatory system. For this reason, people with diabetes are more likely to suffer an ischemic stroke compared to healthy people. This type of stroke is caused by blockage of a blood vessel supplying blood to the brain. In fact, according to some researchers-even up to 30% of ischemic stroke incidents occur in patients with diabetes. In contrast, a meta-analysis of pros...

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