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Clinical trials give patients access to innovative treatments. It doesn't always have to be a last resort

MedExpress Team

Piotr Wójcik

Published April 18, 2024 14:04

Clinical trials give patients access to innovative treatments. It doesn't always have to be a last resort - Header image
fot. Piotr Wójcik
Clinical trials are less and less talked about anymore as the last possible therapy to be implemented or a medical experiment. In fact, it is through them that patients gain access to innovative treatments, not only in the last, but also in the first lines of treatment. The development of the clinical trials market is progressing rapidly, and the regulatory framework is getting closer to harmonization, both at the European and global levels. Experts from the EMA, FDA, Mayo Clinic and NIO-PIB discussed the related challenges at the National Cancer Institute.

- We should look at cancer, which until recently was incurable. In the 1970s we had 40 cancer drugs registered, now about 15 are approved annually in the U.S. In the beginning it was difficult to deal with malignant tumors, and now we have programs that aim to completely eradicate the disease," stressed Prof. Richard Pazdur of the U.S. Food and Drug Administration (FDA).

As Prof. Grzegorz Nowakowski of the Mayo Clinic pointed out, there are already a great many therapies available to improve patients' lives. Their efficacy profiles are increasing, and availability is also increasing, as these therapies are less costly. He cited as an example lymphomas, in which chemotherapy is already being abandoned in favor of immunotherapy. However, there would be no such changes were it not for the fact that new drugs are being developed and tested more and more efficiently.

- We need to conduct extensive evaluation of ...

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